Coseal Surgical Sealant

Coseal Surgical Sealant

Coseal is indicated for use in vascular reconstructions to achieve adjunctive hemostasis by mechanically sealing areas of leakage.

Coseal Surgical Sealant is designed to provide a rapid intraoperative seal at the suture line and to maintain this protection during the critical postoperative period. This allows the body time to complete its natural wound healing process at the anastomosis, supporting the integrity of your work at vascular reconstruction sites that may be at risk for increased bleeding due to:

Coagulopathies

High pressure suture lines

Friable vascular tissue

As a fully synthetic hydrogel, Coseal Surgical Sealant is developed for the right balance of strength, elasticity and time-to-resorption, and is completely free of glutaraldehyde and bovine components.

BURST STRENGTH: Can withstand postoperative spikes over 5x normal systolic pressure at up to 660 [+/- 150] mm Hg (in vitro burst test for closure of puncture defects 0.6-0.9 mm diameter, n=4) in porcine carotid artery.

ELASTICITY: Thin, motion-responsive seal provides biomechanical compatibility and supports natural vascular dilation.

RESORPTION: Resorbed within 30 days of application. Remains at application site for up to 7 days.

Do not inject Coseal into vessels.

Coseal is not to be used in place of sutures, staples, or mechanical closure.

Coseal swells up to four times its volume within 24 hours of application and additional swelling occurs as the gel resorbs. Therefore, surgeons should consider the maximum swell volume and its possible effect on surrounding anatomic structures potentially sensitive to compression.